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KMID : 0191119940090030268
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Journal of Korean Medical Science
1994 Volume.9 No. 3 p.268 ~ p.272
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A case of primary hyperparathyroidism with hypercalcemic nephropathy in children
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Yu JM
Pyo HJ/Choi DS/Lee KW/Yoo KH/Kim CS
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Abstract
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Primary hyperparathyroidism is a rare disease in children and is characterized by conspicuous skeletal and renal changes. A 12 year old male patient presented with symptoms of polydipsia, polyuria, general weakness, nausea, and vomiting which had begun 3 months earlier, and showed typical laboratory findings of primary hyperparathyroidism. Confirmatory diagnosis was made by elevated parathyroid hormone concentration in serum, technetium-thallium subtraction scan imaging method and histopathologic finding of chief cell hyperplasia. The laboratory findings revealed
elevated levels of BUN, creatinine and decreased GFR. Kidney biopsy showed typical calcium deposits in tubules with marked tubulointerstitial infiltration. After subtotal parathyroidectomy,
clinical findings improved remarkably.
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KEYWORD
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